Two winning teams from the American Football Conference (AFC) West will collide Thursday as the Kansas City Chiefs host the Denver Broncos at the Arrowhead Stadium. 

The main factor in this matchup is Broncos veteran quarterback Peyton Manning who has been leading the team since signing in 2012. 

Since Manning joined the Broncos, the Chiefs have failed to get a win over them in six attempts. 

The Broncos are also the reigning division champions (AFC West) for the past four seasons and are looking for a fifth straight. 

"I don't think they necessarily get in our head. Certainly these guys are the division champs since we've all been here together," Chiefs quarterback Alex Smith said, according to NFL.com. 

Smith added that they had chances of winning in their previous matches against the Broncos but just could not get the job done. 

Citing the importance of a win over Denver, the 31-year-old quarterback also said that their goals of winning the division and reaching the playoffs all start with their division. 

Smith will be leading the charge for Kansas City following a great showing in their season opener win over the Houston Texans. He had 22 completions for 243 yards and threw for all the three touchdowns that they scored against Houston. 

Meanwhile, on the Broncos side, Manning is looking to bounce back following their opener against the Baltimore Ravens. 

Denver won the game but only scored one touchdown and Manning was not even involved in the play. 

In the victory against Baltimore, the 39-year-old footballer completed 24 of 40 passes for 175 yards and along with having no touchdown pass, he was also sacked four times. 

The performance against the Ravens was very uncharacteristic of Manning and it will be something the Chiefs would try to expose this Thursday. 

The match between the Kansas City Chiefs and the Denver Broncos will be today, Sept. 17, at 8:25 p.m. EST. 

CBS and the NFL Network will be airing the game. To watch via live stream, click here.