The Buffalo Bills will play the Detroit Lions in the NFL on Sunday with the Lions looking to build on their impressive 3-1 start to the season so far. The Bills meanwhile will be trying to get their season back on track after two straight losses have undermined their 2-0 start to the season, to bring them into Week 5 on 2-2.

Today's game will start at 1 p.m. EST and can be watched on the Fox network. The game can also be watched online through live stream on Direct TV's NFL Sunday Ticket by clicking here.

Today's big match up comes amid news that the NFL will begin on Monday to test players for human growth hormone (HGH).

Earlier in September, the NFL and the NFLPA announced that they had agreed to a new drug policy; that new agreement was widespread but included HGH testing for the first time in the NFL's history.

A letter written by NFLPA president Eric Winston to players has been leaked, and was published on NFL.com.

The letter reads: "As you know, the new Performance Enhancing Substances Policy includes HGH testing. Testing for HGH will begin on Monday, October 6th.

"Each week of the season, 5 players on 8 teams will be tested. No testing will occur on game days. We negotiated to ensure that the methodology of testing be conducted in the most professional and safest manner for players.

"Importantly, after three years of negotiating, players won the right to challenge any aspect of the science behind the HGH isoforms test in an appeal of a positive test."

If any performance enhancing drug policy violations are found, including HGH, the case will then be passed onto and handled by an independent arbitrator.